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Article

Interaction between ACE and ADD1 gene polymorphisms in the progression of IgA nephropathy in Japanese patients.

Hypertension (Dallas, Tex. : 1979) - 1 Sept 2003

Narita Ichiei, Goto Shin, Saito Noriko, Song Jin, Ajiro Junya, Sato Fuminori, Saga Daisuke, Kondo Daisuke, Akazawa Kohei, Sakatsume Minoru, Gejyo Fumitake

Abstract excerpt

An interaction effect between the angiotensin-converting enzyme insertion/deletion (ACE I/D) and alpha-adducin (ADD1) Gly460Trp polymorphisms (G460W) on blood pressure regulation has recently been suggested, although its significance in the prognosis of renal function in IgA nephropathy (IgAN) has not been fully investigated. Therefore, we evaluated the clinical manifestations and renal prognosis in 276 Japanese...

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Identifiers

PMID: 12885793
DOI: 10.1161/01.HYP.0000085193.25617.78

Genes

ACE
ADD1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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