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Article

ACE insertion/deletion polymorphism (rs1799752) modifies the renoprotective effect of renin-angiotensin system blockade in patients with IgA nephropathy.

Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Sept 2015

Teranishi Junya, Yamamoto Ryohei, Nagasawa Yasuyuki, Shoji Tatsuya, Iwatani Hirotsugu, Okada Noriyuki, Moriyama Toshiki, Yamauchi Atsushi, Tsubakihara Yoshiharu, Imai Enyu, Rakugi Hiromi, Isaka Yoshitaka

Abstract excerpt

INTRODUCTION: Little is known about genetic predictors that modify the renoprotective effect of renin-angiotensin system (RAS) blockade in IgA nephropathy (IgAN). MATERIALS AND METHODS: The present multicenter retrospective observational study examined effect modification between RAS blockade and three RAS-related gene polymorphisms in 237 IgAN patients, including ACE I/D (rs1799752), AT1R A1166C (rs5186) and AGT...

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Source

Identifiers

PMID: 24452035
DOI: 10.1177/1470320313515036

Genes

ACE
AGT

Variants

rs1799752
rs1799752

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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