Article
Blood pressure-related genes and the progression of IgA nephropathy.
Nephron. Clinical practice - 1 Jan 2009
Kim Sun Moon, Chin Ho Jun, Oh Yun Kyu, Kim Yon Su, Kim Suhnggwon, Lim Chun Soo
Abstract excerpt
BACKGROUND/AIMS: Hypertension is one of the most significant prognostic factors of immunoglobulin A nephropathy (IgAN). We investigated the role of polymorphisms of hypertension-related genes in the clinical impact of IgAN. METHODS: A total of 238 IgAN and 300 healthy cohorts were studied. The polymorphisms of angiotensinogen (AGT M235T), the angiotensin II type 1 receptor (A1166C), aldosterone synthase (C-344T),...
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