Article
Minimal model-based insulin sensitivity has greater heritability and a different genetic basis than homeostasis model assessment or fasting insulin.
Diabetes - 1 Aug 2003
Bergman Richard N, Zaccaro Daniel J, Watanabe Richard M, Haffner Steven M, Saad Mohammed F, Norris Jill M, Wagenknecht Lynne E, Hokanson James E, Rotter Jerome I, Rich Steven S
Abstract excerpt
Insulin resistance is an important risk factor for development of type 2 diabetes as well as other chronic conditions, including hypertension, cardiovascular disease, and colon cancer. To find genes for insulin resistance it is necessary to assess insulin action in large populations. We have previously measured insulin action in a large cohort of subjects (Insulin Resistance and Atherosclerosis Study [IRAS]...
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