Article
Insulin resistance is the best predictor of the metabolic syndrome in subjects with a first-degree relative with type 2 diabetes.
Obesity (Silver Spring, Md.) - 1 Sept 2010
Utzschneider Kristina M, Van de Lagemaat Anne, Faulenbach Mirjam V, Goedecke Julia H, Carr Darcy B, Boyko Edward J, Fujimoto Wilfred Y, Kahn Steven E
Abstract excerpt
Although obesity is associated with insulin resistance and the metabolic syndrome (MetS), some obese individuals are metabolically healthy. Conversely, some lean individuals are insulin resistant (IR) and at increased cardiometabolic risk. To determine the relative importance of insulin sensitivity, BMI and waist circumference (WC) in predicting MetS, we studied these two extreme groups in a high-risk population....
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