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Article

Multiple cross mapping (MCM) markedly improves the localization of a QTL for ethanol-induced activation.

Genes, brain, and behavior - 1 Nov 2002

Hitzemann R, Malmanger B, Cooper S, Coulombe S, Reed C, Demarest K, Koyner J, Cipp L, Flint J, Talbot C, Rademacher B, Buck K, McCaughran J

Abstract excerpt

This study examines the use of multiple cross mapping (MCM) to reduce the interval for an ethanol response QTL on mouse chromosome 1. The phenotype is the acute locomotor response to a 1.5-g/kg i.p. dose of ethanol. The MCM panel consisted of the six unique intercrosses that can be obtained from the C57BL/6J (B6), DBA/2J (D2), BALB/cJ (C) and LP/J (LP) inbred mouse strains (N > or = 600/cross). Ethanol response...

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Identifiers

PMID: 12882366
DOI: 10.1034/j.1601-183x.2002.10403.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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