Article
Butyrylcholinesterase (BCHE) genotyping for post-succinylcholine apnea in an Australian population.
Clinical chemistry - 1 Aug 2003
Yen Tina, Nightingale Brian N, Burns Jennifer C, Sullivan David R, Stewart Peter M
Abstract excerpt
BACKGROUND: Measurement of plasma butyrylcholinesterase (BChE) activity and inhibitor-based phenotyping are standard methods for identifying patients who experience post-succinylcholine (SC) apnea attributable to inherited variants of the BChE enzyme. Our aim was to develop PCR-based assays for BCHE mutation detection and implement them for routine diagnostic use at a university teaching hospital. METHODS:...
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