Article
Concordance of butyrylcholinesterase phenotype with genotype: implications for biochemical reporting.
American journal of clinical pathology - 1 Feb 2011
Parnas M Laura, Procter Melinda, Schwarz Monica A, Mao Rong, Grenache David G
Abstract excerpt
Butyrylcholinesterase (BChE) metabolizes the paralytic succinylcholine. Extended paralysis occurs in people with inherited BChE variants that may be identified by measuring BChE activity with and without the inhibitor dibucaine to calculate a dibucaine number (DN). Accurate phenotyping requires phenotype-specific BChE and DN reference intervals. We investigated the concordance between the biochemical BChE...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
