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Article

Five new naturally occurring mutations of the BCHE gene and frequencies of 12 butyrylcholinesterase alleles in a Brazilian population.

Pharmacogenetics and genomics - 1 Mar 2008

Mikami Liya R, Wieseler Stacy, Souza Ricardo L R, Schopfer Lawrence M, Nachon Florian, Lockridge Oksana, Chautard-Freire-Maia Eleidi A

Abstract excerpt

Human butyrylcholinesterase (BChE; EC 3.1.1.8) is codified by the BCHE gene (3q26.1-q26.2) in which 65 variants have been identified. BChE is a scavenger of organophosphorus and carbamate compounds and hydrolyzes succinylcholine, mivacurium and cocaine. The present study describes 12 naturally occurring BCHE mutations including five new mutations (K12R, G15G, V294M, G333C and R470W) identified in 366 blood donors...

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Source

Identifiers

PMID: 18300943
DOI: 10.1097/FPC.0b013e3282f5107e

Genes

BCHE
BTC

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Five new naturally occurring mutations of the BCHE gene and frequencies of 12 butyrylcholinesterase alleles in a Brazilian population.PMID 18300943Read ↗

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