Article
Genotyping the butyrylcholinesterase in patients with prolonged neuromuscular block after succinylcholine.
Anesthesiology - 1 Mar 2005
Levano Soledad, Ginz Hans, Siegemund Martin, Filipovic Miodrag, Voronkov Evgueni, Urwyler Albert, Girard Thierry
Abstract excerpt
BACKGROUND: Succinylcholine remains the standard neuromuscular blocking drug for tracheal intubation in emergency situations. The short duration of action is due to its rapid hydrolytic degradation by butyrylcholinesterase (plasmacholinesterase). Multiple variants of this enzyme are known (A, F, S, H, J, K variants) with different effects on enzyme activity. This study was undertaken to evaluate the use of...
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