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Article

BMP regulation of the mouse connexin43 promoter in osteoblastic cells and embryos.

Cell communication & adhesion - 1 Jan 2000

Chatterjee B, Meyer R A, Loredo G A, Coleman C M, Tuan R, Lo C W

Abstract excerpt

We examined BMP regulation of the gap junction gene Gjal (Cx43alpha1) using a series of lacZ reporter constructs containing up to 6.7 kbs of mouse Cx43alpha1 promoter sequence. Using transient transfection assays, we showed that BMP2, BMP4, and GDF5, but not BMP6 or BMP7, can modulate Cx43alpha1 promoter activity in the osteosarcoma cell line ROS17/2.8. Positive regulatory elements were found at the proximal and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12881039
DOI: 10.1080/15419060302064

Genes

GDF5
BMP2
BMP4
BMP6
BMP7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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