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Article

Cardiac fibroblasts influence cardiomyocyte phenotype in vitro.

American journal of physiology. Cell physiology - 1 May 2007

LaFramboise W A, Scalise D, Stoodley P, Graner S R, Guthrie R D, Magovern J A, Becich M J

Abstract excerpt

Cardiac fibroblasts impact myocardial development and remodeling through intercellular contact with cardiomyocytes, but less is known about noncontact, profibrotic signals whereby fibroblasts alter cardiomyocyte behavior. Fibroblasts and cardiomyocytes were harvested from newborn rat ventricles and separated by serial digestion and gradient centrifugation. Cardiomyocytes were cultured in 1) standard medium, 2)...

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Identifiers

PMID: 17229813
DOI: 10.1152/ajpcell.00166.2006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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