Article
Cardiomyocytes fuse with surrounding noncardiomyocytes and reenter the cell cycle.
The Journal of cell biology - 25 Oct 2004
Matsuura Katsuhisa, Wada Hiroshi, Nagai Toshio, Iijima Yoshihiro, Minamino Tohru, Sano Masanori, Akazawa Hiroshi, Molkentin Jeffery D, Kasanuki Hiroshi, Komuro Issei
Abstract excerpt
The concept of the plasticity or transdifferentiation of adult stem cells has been challenged by the phenomenon of cell fusion. In this work, we examined whether neonatal cardiomyocytes fuse with various somatic cells including endothelial cells, cardiac fibroblasts, bone marrow cells, and endothelial progenitor cells spontaneously in vitro. When cardiomyocytes were cocultured with endothelial cells or cardiac...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
