Article
Human adult skeletal muscle stem cells differentiate into cardiomyocyte phenotype in vitro.
Experimental cell research - 15 Jan 2008
Invernici Gloria, Cristini Silvia, Madeddu Paolo, Brock Stefano, Spillmann Frank, Bernasconi Pia, Cappelletti Cristina, Calatozzolo Chiara, Fascio Umberto, Bisleri Gianluigi, Muneretto Claudio, Alessandri Giulio, Parati Eugenio A
Abstract excerpt
Cell transplantation to repair or regenerate injured myocardium is a new frontier in the treatment of cardiovascular disease. Most studies on stem cell transplantation therapy in both experimental heart infarct and in phase-I human clinical trials have focused on the use of undifferentiated stem cells. Based on our previous observations demonstrating the presence of multipotent progenitor cells in human adult...
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