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Article

Inhibition of human m-epoxide hydrolase gene expression in a case of hypercholanemia.

Biochimica et biophysica acta - 30 Jul 2003

Zhu Qin-shi, Xing Wenxue, Qian Bin, von Dippe Patricia, Shneider Benjamin L, Fox Victor L, Levy Daniel

Abstract excerpt

Microsomal epoxide hydrolase (mEH) is a bifunctional protein that plays a central role in carcinogen metabolism and is also able to mediate the sodium-dependent uptake of bile acids into hepatocytes. Studies have identified a subject (S-1) with extremely elevated serum bile salt levels in the abs...

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Source

Identifiers

PMID: 12878321
DOI: 10.1016/s0925-4439(03)00085-1

Genes

EPHX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12878321-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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