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Article

Cytochrome P450 1B1, a new keystone in gene-environment interactions related to human head and neck cancer?

Archives of toxicology - 1 Jun 2002

Thier Ricarda, Brüning Thomas, Roos Peter H, Bolt Hermann M

Abstract excerpt

Alcohol consumption and tobacco smoking are major causes of head and neck cancers, and regional differences point to the importance of research into gene-environment interactions. Much interest has been focused on polymorphisms of CYP1A1 and of GSTM1 and GSTT1, but a number of studies have not demonstrated significant effects. This has mostly been ascribed to small sample sizes. In general, the impact of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12107641
DOI: 10.1007/s00204-002-0349-3

Genes

PAH
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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