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Article

The TCA cycle is not required for selection or survival of multidrug-resistant Salmonella.

The Journal of antimicrobial chemotherapy - 1 Mar 2012

Ricci Vito, Loman Nick, Pallen Mark, Ivens Alasdair, Fookes Maria, Langridge Gemma C, Wain John, Piddock Laura J V

Abstract excerpt

OBJECTIVES: The initial aim of this study was to use a systems biology approach to analyse a ciprofloxacin-selected multidrug-resistant (MDR) Salmonella enterica serotype Typhimurium, L664. METHODS: The whole genome sequence and transcriptome of L664 were analysed. Site-directed mutagenesis to recreate each mutation was carried out, followed by phenotypic characterization and mutation frequency analysis. As a...

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Identifiers

PMID: 22186876
DOI: 10.1093/jac/dkr515
PMCID: PMC4125622

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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