Article
Phagocytosis by dendritic cells rather than MHC IIhigh macrophages is associated with skin tumour regression.
International journal of cancer - 20 Sept 2003
Byrne Scott N, Halliday Gary M
Abstract excerpt
Dendritic cells (DC) are important for the induction of anti-tumour immunity and are currently being used in clinical trials. Whether DC in tumours behave the same as DC in normal tissues or whether the tumours subvert DC phenotype and function remains unknown. To address this, we have used a unique animal tumour model to compare the DC infiltrating regressing tumours with the DC infiltrating progressing skin...
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