The interplay of phenotype and genotype in Cryptococcus neoformans disease.

doi:10.1042/BSR20190337

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Article

The interplay of phenotype and genotype in Cryptococcus neoformans disease.

Bioscience reports - 30 Oct 2020

Altamirano Sophie, Jackson Katrina M, Nielsen Kirsten

Abstract excerpt

Cryptococcus neoformans is an opportunistic fungal pathogen that causes life-threatening meningitis primarily in immunocompromised individuals. In order to survive and proliferate during infection, C. neoformans must adapt to a variety of stresses it encounters within the host. Patient outcome de...

Topics

Cryptococcosis
Cryptococcus neoformans
Disease Progression
Evolution, Molecular
Genotype
Host-Pathogen Interactions
Humans
Phenotype
Prognosis
Virulence
Virulence Factors

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