Article
Apolipoprotein E3Basel: new insights into a highly conserved protein region.
European journal of clinical investigation - 1 Aug 2003
Miserez A R, Scharnagl H, Muller P Y, Mirsaidi R, Stähelin H B, Monsch A, März W, Hoffmann M M
Abstract excerpt
BACKGROUND: Apolipoprotein E is important for the receptor-mediated uptake of triglyceride-rich lipoproteins. Mutations in the gene encoding apolipoprotein E may cause a reduced uptake of these lipoproteins. Particular apolipoprotein E mutations have been also found to be associated with nephrologic, neurologic, and even ophthalmologic diseases. Hence, a continuously expanding role in biology is being attributed...
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