Article
The apolipoprotein B Q3405E polymorphism has no effect on its low-density-lipoprotein receptor binding affinity.
Human genetics - 1 Dec 1996
Pullinger C R, Love J A, Liu W, Hennessy L K, Ghassemzadeh M, Newcomb K C, Illingworth D R, Kane J P
Abstract excerpt
A better understanding of the apolipoprotein B100 (apoB100) sequences involved in binding to the low-density lipoprotein (LDL) receptor will be achieved by studying the effects of polymorphisms and rare mutations of apoB100. Upon re-examination of apoB100 DNA sequencing discrepancies, a charge-ch...
Topics
- Alleles
- Apolipoproteins B
- Binding, Competitive
- Glutamic Acid
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Receptors, LDL