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Article

Lipoprotein lipase domain function.

The Journal of biological chemistry - 8 Apr 1994

Wong H, Davis R C, Thuren T, Goers J W, Nikazy J, Waite M, Schotz M C

Abstract excerpt

Human lipoprotein lipase (LPL) monomer consists of two domains, a larger NH2-terminal domain that contains catalytic residues and a smaller COOH-terminal domain that modulates substrate specificity and is a major determinant of heparin binding. Analyses of NH2-terminal domain function were performed after site-directed mutagenesis of the putative active-site serine residue, while COOH-terminal domain function was...

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Identifiers

PMID: 8144612

Genes

LPL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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