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Article

Use of RNA interference and complementation to study the function of the Drosophila and human 26S proteasome subunit S13.

Molecular and cellular biology - 1 Aug 2003

Lundgren Josefin, Masson Patrick, Realini Claudio A, Young Patrick

Abstract excerpt

The S13 subunit (also called Pad1, Rpn11, and MPR1) is a component of the 19S complex, a regulatory complex essential for the ubiquitin-dependent proteolytic activity of the 26S proteasome. To address the functional role of S13, we combined double-stranded RNA interference (RNAi) against the Drosophila proteasome subunit DmS13 with expression of wild-type and mutant forms of the homologous human gene, HS13. These...

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Identifiers

PMID: 12861018
DOI: 10.1128/MCB.23.15.5320-5330.2003
PMCID: PMC165711

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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