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Article

A proteasome assembly defect in rpn3 mutants is associated with Rpn11 instability and increased sensitivity to stress.

Journal of molecular biology - 15 Jul 2011

Joshi Kishore Kumar, Chen Li, Torres Nidza, Tournier Vincent, Madura Kiran

Abstract excerpt

Rpn11 is a proteasome-associated deubiquitinating enzyme that is essential for viability. Recent genetic studies showed that Rpn11 is functionally linked to Rpn10, a major multiubiquitin chain binding receptor in the proteasome. Mutations in Rpn11 and Rpn10 can reduce the level and/or stability of proteasomes, indicating that both proteins influence its structural integrity. To characterize the properties of...

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Identifiers

PMID: 21619884
DOI: 10.1016/j.jmb.2011.05.005
PMCID: PMC3763486

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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