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Article

A new role of Pro-73 of p47phox in the activation of neutrophil NADPH oxidase.

Archives of biochemistry and biophysics - 1 Aug 2003

Nagasawa Teruaki, Ebisu Kentaro, Inoue Yasuyuki, Miyano Kei, Tamura Minoru

Abstract excerpt

The PX domain of p47phox is thought to be involved in autoinhibition. However, when the domain was deleted, the ability to activate the phagocyte NADPH oxidase was markedly diminished. We have mutated the proline-rich region of the PX domain and examined the mutants for the ability to activate. S...

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PMID: 12859985
DOI: 10.1016/s0003-9861(03)00296-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12859985-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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A new role of Pro-73 of p47phox in the activation of neutrophil NADPH oxidase.PMID 12859985Read ↗

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