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Article

NOX Activation by Subunit Interaction and Underlying Mechanisms in Disease

10 Jan 2017

Abstract excerpt

Nicotinamide adenine dinucleotide phosphate (NAPDH) oxidase (NOX) is an enzyme complex with the sole function of producing superoxide anion and reactive oxygen species (ROS) at the expense of NADPH. Vital to the immune system as well as cellular signaling, NOX is also involved in the pathologies of a wide variety of disease states. Particularly, it an integral player in many neurological diseases, including...

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PMID: 28119569
DOI: 10.3389/fncel.2016.00301

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