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Article

Synergistic effect of Helicobacter pylori virulence factors and interleukin-1 polymorphisms for the development of severe histological changes in the gastric mucosa.

The Journal of infectious diseases - 15 Jul 2003

Rad Roland, Prinz Christian, Neu Bruno, Neuhofer Mathilde, Zeitner Marco, Voland Petra, Becker Ingrid, Schepp Wolfgang, Gerhard Markus

Abstract excerpt

Polymorphisms of the IL-1B and IL-1RN genes (which encode interleukin [IL]-1beta and IL-1 receptor antagonist, respectively) have been associated with hypochlorhydria and gastric cancer. We investigated the influence of bacterial virulence factors and host IL-1 polymorphisms on the development of...

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Source

Identifiers

PMID: 12854083
DOI: 10.1086/376458

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12854083-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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