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Article

Integrated virulence-resistance profiling of Helicobacter pylori reveals context-dependent pathogenic signatures in gastric cancer.

Frontiers in cellular and infection microbiology - 1 Jan 2026

Mbuthia Oliver, Mehmood Azhar, Mahjabeen Ishrat, Kayani Mahmood A, Obiero Jael, Matsumoto Takashi, Bosire Kefa, Mureithi Marianne W

Abstract excerpt

Background: Helicobacter pylori contributes to gastric carcinogenesis through diverse virulence mechanisms, transcriptional plasticity, and rising antimicrobial resistance. However, how these features integrate into coordinated bacterial states within the tumor microenvironment remains unclear. This study integrates virulence, expression, and antimicrobial signatures to define potentially meaningful H. pylori...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42239538
DOI: 10.3389/fcimb.2026.1812371
PMCID: PMC13226509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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