Article
Synergistic effect of IL-1β and TNF-α polymorphisms on the H. pylori-related gastric pre-malignant condition.
Hepato-gastroenterology - 1 Jan 2000
Tahara Tomomitsu, Shibata Tomoyuki, Yamashita Hiromi, Yoshioka Daisuke, Okubo Masaaki, Yonemura Joh, Kamiya Yoshio, Ishizuka Takamitsu, Nakagawa Yoshihito, Nagasaka Mitsuo, Iwata Masami, Nakamura Masakatsu, Hirata Ichiro, Arisawa Tomiyasu
Abstract excerpt
BACKGROUND/AIMS: We investigated the effect of IL-1β and TNF-α polymorphisms, and its synergistic effect with age, gender and H. pylori status on the gastric pre-malignant condition. METHODOLOGY: IL-1β-31(T>C) and -511(C>T) and TNF-α-857 (C>T) polymorphisms were genotyped in 123 cancer free subjects. Degree of histological gastritis in both antrum and corpus, and extension of endoscopic gastric atrophy were also...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.