Article
Assessing functional divergence in EF-1alpha and its paralogs in eukaryotes and archaebacteria.
Nucleic acids research - 15 Jul 2003
Inagaki Yuji, Blouin Christian, Susko Edward, Roger Andrew J
Abstract excerpt
A number of methods have recently been published that use phylogenetic information extracted from large multiple sequence alignments to detect sites that have changed properties in related protein families. In this study we use such methods to assess functional divergence between eukaryotic EF-1alpha (eEF-1alpha), archaebacterial EF-1alpha (aEF-1alpha) and two eukaryote-specific EF-1alpha paralogs-eukaryotic...
Topics
- Amino Acid Sequence
- Animals
- Archaea
- Bacteria
- Binding Sites
- DNA, Complementary
- DNA, Protozoan
- Dictyostelium
- Diplomonadida
- Eukaryotic Cells
- Genetic Variation