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Extreme Deviations from Expected Evolutionary Rates in Archaeal Protein Families.

Genome biology and evolution - 1 Oct 2017

Petitjean Celine, Makarova Kira S, Wolf Yuri I, Koonin Eugene V

Abstract excerpt

Origin of new biological functions is a complex phenomenon ranging from single-nucleotide substitutions to the gain of new genes via horizontal gene transfer or duplication. Neofunctionalization and subfunctionalization of proteins is often attributed to the emergence of paralogs that are subject to relaxed purifying selection or positive selection and thus evolve at accelerated rates. Such phenomena potentially...

Topics

Archaea
Archaeal Proteins
Cluster Analysis
Computational Biology
Evolution, Molecular
Gene Duplication
Genes, Archaeal
Genes, Essential
Genetic Speciation
Genetic Variation
Genome, Archaeal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Models, Genetic

Phylogeny

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Identifiers

PMID: 28985292
DOI: 10.1093/gbe/evx189
PMCID: PMC5737733

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