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Article

Tumor necrosis factor-alpha promoter gene polymorphism -308 and chorioamnionitis.

Obstetrics and gynecology - 1 Jul 2003

Simhan Hyagriv N, Krohn Marijane A, Zeevi Adriana, Daftary Ashi, Harger Gail, Caritis Steve N

Abstract excerpt

OBJECTIVE: A single-base polymorphism within the promoter of the gene for tumor necrosis factor alpha at position -308 relative to the transcriptional start site of the gene is correlated with differences in production of tumor necrosis factor alpha. There are two allelic forms: TNFA1 and TNFA2. The TNFA2 allele is associated with increased production of tumor necrosis factor alpha. The purpose of this study is...

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Identifiers

PMID: 12850624
DOI: 10.1016/s0029-7844(03)00406-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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