Article
Tumor necrosis factor-alpha allele lymphotoxin-alpha+250 is associated with the presence and severity of placental inflammation among preterm births.
Pediatric research - 1 Jul 2004
Kazzi S Nadya J, Jacques Suzanne M, Qureshi Faisal, Quasney Michael W, Kim U Olivia, Buhimschi Irina A
Abstract excerpt
Histologic inflammation of placenta has been associated with increased risk for bronchopulmonary dysplasia and periventricular leukomalacia among preterm infants. Tumor necrosis factor-alpha (TNF-alpha) plays a central role in the regulation of inflammation. Some alleles of TNF (LT-alpha+250, TNF-alpha-308, and TNF-alpha-238) have been associated with susceptibility and/or severity of many diseases characterized...
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