Article
A promoter mutation that increases transcription of the tumor necrosis factor-alpha gene is not associated with preterm delivery.
American journal of obstetrics and gynecology - 1 Oct 1997
Dizon-Townson D S, Major H, Varner M, Ward K
Abstract excerpt
OBJECTIVE: Increased amniotic fluid concentrations of tumor necrosis factor-alpha are observed in women with preterm labor and subsequent preterm birth. We tested whether a mutation in the promoter region of tumor necrosis factor-alpha gene, TNF T2, which increases transcription of the gene, is more frequent in a preterm delivery cohort. STUDY DESIGN: Deoxyribonucleic acid was extracted from whole blood of 203...
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