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Article

Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespan.

The Journal of cell biology - 7 Jul 2003

Muro Andres F, Chauhan Anil K, Gajovic Srecko, Iaconcig Alessandra, Porro Fabiola, Stanta Giorgio, Baralle Francisco E

Abstract excerpt

Fibronectins (FNs) are multifunctional high molecular weight glycoproteins present in the blood plasma and in the ECMs of tissues. The FN primary transcript undergoes alternative splicing in three regions generating up to 20 main different variants in humans. However, the precise role of the FN isoforms is poorly understood. One of the alternatively spliced exons is the extra domain A (EDA) or extra type III...

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Source

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Identifiers

PMID: 12847088
DOI: 10.1083/jcb.200212079
PMCID: PMC2172721

Genes

EDA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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