Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

EDA targets revealed by skin gene expression profiles of wild-type, Tabby and Tabby EDA-A1 transgenic mice.

Human molecular genetics - 15 Jul 2002

Cui Chang-Yi, Durmowicz Meredith, Tanaka Tetsuya S, Hartung Andrew J, Tezuka Tadashi, Hashimoto Ken, Ko Minoru S H, Srivastava Anand K, Schlessinger David

Abstract excerpt

Mutations in the EDA gene cause anhidrotic ectodermal dysplasia (EDA), with lesions in skin appendage formation. To begin to analyze EDA pathways, we have used expression profiling on 15,000-gene mouse cDNA microarrays, comparing adult mouse skin from wild-type, EDA-defective (Tabby) mice, and Ta...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ectodermal Dysplasia
Share to Ectodysplasins
Share to JNK Mitogen-Activated Protein Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mitogen-Activated Protein Kinases

Share to NF-kappa B

Share to Oligonucleotide Array Sequence Analysis

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Identifiers

PMID: 12095918
DOI: 10.1093/hmg/11.15.1763

Genes

EDA
SPARC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12095918-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

EDA targets revealed by skin gene expression profiles of wild-type, Tabby and Tabby EDA-A1 transgenic mice.PMID 12095918Read ↗

Candidate EDA targets revealed by expression profiling of primary keratinocytes from Tabby mutant mice.Semantic proximity Read ↗

Inducible mEDA-A1 transgene mediates sebaceous gland hyperplasia and differential formation of two types of mouse hair folliclesSemantic proximity Read ↗

Ectodysplasin-A1 is sufficient to rescue both hair growth and sweat glands in Tabby miceSemantic proximity Read ↗

The Tabby phenotype is caused by mutation in a mouse homologue of the EDA gene that reveals novel mouse and human exons and encodes a protein (ectodysplasin-A) with collagenous domains.Semantic proximity Read ↗

X-linked anhidrotic ectodermal dysplasia disruption yields a mouse model for ocular surface disease and resultant blindness.Semantic proximity Read ↗

Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm.Semantic proximity Read ↗

Ectodysplasin regulates the lymphotoxin-beta pathway for hair differentiation.Semantic proximity Read ↗

Regulation of hair follicle development by the TNF signal ectodysplasin and its receptor Edar.Semantic proximity Read ↗

Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespan.Semantic proximity Read ↗

Molecular aspects of hypohidrotic ectodermal dysplasia.Semantic proximity Read ↗

Identification of a new splice form of the EDA1 gene permits detection of nearly all X-linked hypohidrotic ectodermal dysplasia mutations.Semantic proximity Read ↗

The anhidrotic ectodermal dysplasia gene (EDA) undergoes alternative splicing and encodes ectodysplasin-A with deletion mutations in collagenous repeats.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.