Article
Biological relevance of the polymorphism in the CCR5 gene in refractory and non-refractory rheumatoid arthritis in Mexicans.
Clinical and experimental rheumatology - 1 Jan 2000
Zúñiga J A, Villarreal-Garza C, Flores E, Barquera R, Pérez-Hernández N, Montes de Oca J V, Cardiel M H, Vargas-Alarcón G, Granados J
Abstract excerpt
OBJECTIVE: The aim of this study was to analyze the frequencies of the CCR5 delta 32 deletion and HLA class II alleles in Mexican Amerindian populations and its relevance in the development and severity of RA. METHODS: We studied 212 Mexican Mestizo subjects (40 patients with refractory RA, 102 patients with non-refractory RA and 70 healthy individuals). At the same time, to evaluate the ethnicity of the CCR5...
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