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Article

Identification and developmental expression of the Xenopus laevis cystic fibrosis transmembrane conductance regulator gene

1 Jan 1992

Abstract excerpt

An amphibian homologue of the human cystic fibrosis transmembrane conductance regulator (CFTR) gene has been isolated from Xenopus laevis by polymerase chain reaction (PCR) amplification. The 4455bp sequence encodes a predicted polypeptide of 1485 amino acids which has an overall homology at the amino acid level of 77% identity and 88% similarity with human CFTR. Comparison of these evolutionarily diverse CFTR...

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PMID: 1284470
DOI: 10.1093/hmg/1.2.77

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