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Article

Xenopus: An emerging model for studying congenital heart disease

28 Apr 2011

Abstract excerpt

Congenital heart defects affect nearly 1% of all newborns and are a significant cause of infant death. Clinical studies have identified a number of congenital heart syndromes associated with mutations in genes that are involved in the complex process of cardiogenesis. The African clawed frog, Xenopus, has been instrumental in studies of vertebrate heart development and provides a valuable tool to investigate the...

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PMID: 21538812
DOI: 10.1002/bdra.20793

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