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Article

Artemisinin autoinduction is caused by involvement of cytochrome P450 2B6 but not 2C9.

Clinical pharmacology and therapeutics - 1 Jul 2003

Simonsson Ulrika S H, Jansson Britt, Hai Trinh Ngoc, Huong Dinh Xuan, Tybring Gunnel, Ashton Michael

Abstract excerpt

AIM: Our goal was to investigate whether artemisinin autoinduction is caused by an increase in cytochrome P450 (CYP) 2B6 or CYP2C9 activities, we evaluated the effects of multiple-dose artemisinin administration on S-mephenytoin N-demethylation in healthy subjects. METHODS: Fourteen subjects, 6 p...

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Source

Identifiers

PMID: 12844133
DOI: 10.1016/S0009-9236(03)00092-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12844133-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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