Article
Roles of peroxisome proliferator-activated receptors delta and gamma in myoblast transdifferentiation.
Experimental cell research - 1 Aug 2003
Holst Dorte, Luquet Serge, Kristiansen Karsten, Grimaldi Paul A
Abstract excerpt
Dietary long chain fatty acids and thiazolidinediones act as potent activators of adipogenesis in established preadipose cell lines. High concentrations of thiazolidinediones have also been shown to induce terminal differentiation of non-preadipose cells, such as fibroblasts and myoblasts, into adipose-like cells. This transdifferentiation was observed in both rodent and human myoblasts. In this report, we show...
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