Article
Relation between apolipoprotein E genotype, hepatitis B virus status, and thyroid status in a sample of older persons with Down syndrome.
American journal of medical genetics. Part A - 15 Jul 2003
Percy Maire E, Potyomkina Zoya, Dalton Arthur J, Fedor Bettye, Mehta Pankaj, Andrews David F, Mazzulli Tony, Murk Lillian, Warren Andrew C, Wallace Robyn A, Chau Hien, Jeng Winnie, Moalem Sharon, O'Brien Lisa, Schellenberger Sonia, Tran Helen, Wu Linda
Abstract excerpt
Dementia of the Alzheimer type (DAT) is common in older persons with Down syndrome (DS). There are three common alleles of the apolipoprotein E (ApoE) gene (Sigma 2, Sigma 3, and Sigma 4) resulting in three different isoforms (E2, E3, and E4) and six different genotypes (2,2; 2,3; 2,4; 3,3; 3,4;...
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