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Article

Inhibition of Egr-1 expression reverses transformation of prostate cancer cells in vitro and in vivo.

Oncogene - 3 Jul 2003

Baron Véronique, De Gregorio Giorgia, Krones-Herzig Anja, Virolle Thierry, Calogero Antonella, Urcis Rafael, Mercola Dan

Abstract excerpt

Transcription factor early growth response-1 (Egr-1) is a crucial regulator of cell growth, differentiation and survival. Several observations suggest that Egr-1 is growth promoting in prostate cancer cells and that blocking its function may impede cancer progression. To test this hypothesis, we...

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Source

Identifiers

PMID: 12833142
DOI: 10.1038/sj.onc.1206560

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12833142-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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