Article
Early growth response-1 gene: potential radiation response gene marker in prostate cancer.
American journal of clinical oncology - 1 Oct 2001
Ahmed M M, Chendil D, Lele S, Venkatasubbarao K, Dey S, Ritter M, Rowland R G, Mohiuddin M
Abstract excerpt
This study was undertaken to determine whether the transcription factor EGR-1 expression: (1) in the primary tumor, correlates with radiation response in terms of complete local tumor control with no evidence of disease or recurrence and no evidence of metastasis; (2) in the postirradiated biopsies correlates with residual tumor; and (3) correlates with the expression of Egr-1 target genes such as TP53, pRB, and...
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