Article
Antisense inhibition of the PTI-1 oncogene reverses cancer phenotypes.
Proceedings of the National Academy of Sciences of the United States of America - 17 Feb 1998
Su Z, Goldstein N I, Fisher P B
Abstract excerpt
The genetic alterations and molecular events mediating human prostate cancer development and progression remain to be defined. Rapid expression cloning and differential RNA display detect a putative oncogene, prostate tumor-inducing gene 1 (PTI-1), that is differentially expressed in human prostate (as well as breast, colon, and small cell lung) cancer cell lines, patient-derived prostate carcinomas, and blood...
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