Article
EGR1 target genes in prostate carcinoma cells identified by microarray analysis.
The Journal of biological chemistry - 8 Dec 2000
Svaren J, Ehrig T, Abdulkadir S A, Ehrengruber M U, Watson M A, Milbrandt J
Abstract excerpt
The EGR1 transactivator is overexpressed in prostate cancer, and its expression pattern suggests that EGR1 could potentially regulate a number of steps involved in initiation and progression of prostate cancer, such as mitogenesis, invasiveness, angiogenesis, and metastasis. To identify potential EGR1 target genes in an unbiased manner, we have utilized adenovirus-mediated expression of EGR1 in a prostate cancer...
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