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Article

Phosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activity.

Molecular and cellular biology - 1 Jul 2003

Roux Philippe P, Richards Stephanie A, Blenis John

Abstract excerpt

Stimulation of the Ras/extracellular signal-regulated kinase (ERK) pathway can modulate cell growth, proliferation, survival, and motility. The p90 ribosomal S6 kinases (RSKs) comprise a family of serine/threonine kinases that lie at the terminus of the ERK pathway. Efficient RSK activation by ERK requires its interaction through a docking site located near the C terminus of RSK, but the regulation of this...

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Identifiers

PMID: 12832467
DOI: 10.1128/MCB.23.14.4796-4804.2003
PMCID: PMC162206

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Source receipt: pubmed, retrieved 7 Sept 2026.

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