Article
The murine telomerase catalytic subunit shares the PAb-240 mutant specific epitope of the p53 protein.
FEBS letters - 10 Jul 2003
Shats Igor, Milyavsky Michael, Erez Neta, Rotter Varda
Abstract excerpt
Many tumorigenic p53 mutants gain a common antigenic epitope that is recognized by the PAb-240 antibody. Database search identified the presence of this epitope in several other proteins, including several antibodies and the catalytic subunit of mouse telomerase, mTERT. These antibodies may represent a part of the previously demonstrated anti-idiotypic network built around p53. In the present study we demonstrate...
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