Article
The pore helix is involved in stabilizing the open state of inwardly rectifying K+ channels.
Biophysical journal - 1 Jul 2003
Alagem Noga, Yesylevskyy Semen, Reuveny Eitan
Abstract excerpt
Ion channels can be gated by various extrinsic cues, such as voltage, pH, and second messengers. However, most ion channels display extrinsic cue-independent transitions as well. These events represent spontaneous conformational changes of the channel protein. The molecular basis for spontaneous...
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