Article
Local synthesis of the rat Vasopressin precursor in dendrites of in vitro cultured nerve cells.
Brain research. Molecular brain research - 10 Jun 2003
Mohr Evita, Richter Dietmar
Abstract excerpt
Vasopressin (VP) mRNA is subject to dendritic targeting both in vivo and in primary cultured neurons microinjected with an appropriate expression vector. We have constructed a vector encoding the mutant Brattleboro rat VP precursor which is non-diffusable, because it cannot leave the site of its synthesis, the rough endoplasmic reticulum. Expression of this construct in cultured nerve cells shows that the mutant...
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